Fitness cost of mcr-1-mediated polymyxin resistance in Klebsiella pneumoniae

OBJECTIVES: The discovery of mobile colistin resistance mcr-1, a plasmid-borne polymyxin resistance gene, highlights the potential for widespread resistance to the last-line polymyxins. In the present study, we investigated the impact of mcr-1 acquisition on polymyxin resistance and biological fitne...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Antimicrob Chemother
Hauptverfasser: Nang, Sue C, Morris, Faye C, McDonald, Michael J, Han, Mei-Ling, Wang, Jiping, Strugnell, Richard A, Velkov, Tony, Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6693033/
https://ncbi.nlm.nih.gov/pubmed/29514208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky061
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