ImmunoPET Imaging of Endogenous and Transfected Prolactin Receptor Tumor Xenografts

Antibodies labeled with positron-emitting isotopes have been used for tumor detection, predicting which patients may respond to tumor antigen-directed therapy, and assessing pharmacodynamic effects of drug interventions. Prolactin receptor (PRLR) is overexpressed in breast and prostate cancers and i...

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Veröffentlicht in:Mol Pharm
Hauptverfasser: Cheal, Sarah M., Ruan, Shutian, Veach, Darren R., Longo, Valerie A., Punzalan, Blesida J., Wu, Jiong, Fung, Edward K., Kelly, Marcus P., Kirshner, Jessica R., Giurleo, Jason T., Ehrlich, George, Han, Amy Q., Thurston, Gavin, Olson, William C., Zanzonico, Pat B., Larson, Steven M., Carrasquillo, Jorge A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692913/
https://ncbi.nlm.nih.gov/pubmed/29684277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b01133
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