Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial

BACKGROUND: Diffuse intrinsic pontine glioma is one of the deadliest central nervous system tumours of childhood, with a median overall survival of less than 12 months. Convection-enhanced delivery has been proposed as a means to efficiently deliver therapeutic agents directly into the brainstem whi...

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Detalhes bibliográficos
Publicado no:Lancet Oncol
Main Authors: Souweidane, Mark M, Kramer, Kim, Pandit-Taskar, Neeta, Zhou, Zhiping, Haque, Sofia, Zanzonico, Pat, Carrasquillo, Jorge A, Lyashchenko, Serge K, Thakur, Sunitha B, Donzelli, Maria, Turner, Ryan S, Lewis, Jason S, Cheung, Nai-Kong V, Larson, Steven M, Dunkel, Ira J
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692905/
https://ncbi.nlm.nih.gov/pubmed/29914796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(18)30322-X
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