Lysyl oxidase-like 2 depletion is protective in age-associated vascular stiffening

Vascular stiffening and its sequelae are major causes of morbidity and mortality in the elderly. The increasingly accepted concept of “smooth muscle cell (SMC) stiffness syndrome” along with matrix deposition has emerged in vascular biology to account for the mechanical phenotype of arterial aging,...

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Pubblicato in:Am J Physiol Heart Circ Physiol
Autori principali: Steppan, Jochen, Wang, Huilei, Bergman, Yehudit, Rauer, Marcel J., Tan, Siqi, Jandu, Sandeep, Nandakumar, Kavitha, Barreto-Ortiz, Sebastian, Cole, Robert N., Boronina, Tatiana N., Zhu, Wanqu, Halushka, Marc K., An, Steven S., Berkowitz, Dan E., Santhanam, Lakshmi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692735/
https://ncbi.nlm.nih.gov/pubmed/31002285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00670.2018
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