Early podocyte injury and elevated levels of urinary podocyte-derived extracellular vesicles in swine with metabolic syndrome: role of podocyte mitochondria

Metabolic syndrome (MetS) is associated with nutrient surplus and kidney hyperfiltration, accelerating chronic renal failure. The potential involvement of podocyte damage in early MetS remains unclear. Mitochondrial dysfunction is an important determinant of renal damage, but whether it contributes...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Zhang, Li-Hong, Zhu, Xiang-Yang, Eirin, Alfonso, Nargesi, Arash Aghajani, Woollard, John R., Santelli, Adrian, Sun, In O., Textor, Stephen C., Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692726/
https://ncbi.nlm.nih.gov/pubmed/31042059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00399.2018
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