THE METABOLIC SYNDROME INDUCES EARLY CHANGES IN THE SWINE RENAL MEDULLARY MITOCHONDRIA

The metabolic syndrome (MetS) is associated with nutrient surplus and kidney hyperfiltration, accelerating chronic renal failure. Mitochondria can be overwhelmed by substrate excess, leading to inefficient energy production and thereby tissue hypoxia. Mitochondrial dysfunction is emerging as an impo...

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Detalhes bibliográficos
Publicado no:Transl Res
Main Authors: Eirin, Alfonso, Woollard, John R., Ferguson, Christopher M., Jordan, Kyra L., Tang, Hui, Textor, Stephen C., Lerman, Amir, Lerman, Lilach O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429873/
https://ncbi.nlm.nih.gov/pubmed/28363084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.03.002
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