THE METABOLIC SYNDROME INDUCES EARLY CHANGES IN THE SWINE RENAL MEDULLARY MITOCHONDRIA

The metabolic syndrome (MetS) is associated with nutrient surplus and kidney hyperfiltration, accelerating chronic renal failure. Mitochondria can be overwhelmed by substrate excess, leading to inefficient energy production and thereby tissue hypoxia. Mitochondrial dysfunction is emerging as an impo...

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Détails bibliographiques
Publié dans:Transl Res
Auteurs principaux: Eirin, Alfonso, Woollard, John R., Ferguson, Christopher M., Jordan, Kyra L., Tang, Hui, Textor, Stephen C., Lerman, Amir, Lerman, Lilach O.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429873/
https://ncbi.nlm.nih.gov/pubmed/28363084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trsl.2017.03.002
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