Inhibition of polycomb repressor complex 2 ameliorates neointimal hyperplasia by suppressing trimethylation of H3K27 in vascular smooth muscle cells

BACKGROUND AND PURPOSE: The increased proliferation and migration of vascular smooth muscle cells (VSMCs) after arterial injury contributes greatly to the pathogenesis of neointimal hyperplasia. As a major component of epigenetics, histone methylation plays an important role in several cardiovascula...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Liang, Jing, Li, Qi, Cai, Wenbin, Zhang, Xuejiao, Yang, Bing, Li, Xin, Jiang, Shuai, Tian, Shanshan, Zhang, Kai, Song, Hao, Ai, Ding, Zhang, Xu, Wang, Chunjiong, Zhu, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692584/
https://ncbi.nlm.nih.gov/pubmed/31162630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14754
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