Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer

Valine catabolism is known to be essential for cancer cells but the detailed mechanism remains unclear. This study is to explore the critical roles of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) in colorectal cancers (CRC) and to develop a new therapy returning valine metabolism homeostasis. High HIBC...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Shan, Yunlong, Gao, Yuan, Jin, Wei, Fan, Minmin, Wang, Ying, Gu, Yanhong, Shan, Chenxiao, Sun, Lijun, Li, Xin, Yu, Biao, Luo, Qiong, Xu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692300/
https://ncbi.nlm.nih.gov/pubmed/31409769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1832-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados