Efficacy and safety of bimekizumab as add-on therapy for rheumatoid arthritis in patients with inadequate response to certolizumab pegol: a proof-of-concept study

OBJECTIVE: Evaluate the efficacy and safety of dual neutralisation of interleukin (IL)-17A and IL-17F with bimekizumab, a monoclonal IgG1 antibody, in addition to certolizumab pegol (CZP) in patients with rheumatoid arthritis (RA) and inadequate response (IR) to certolizumab pegol. METHODS: During t...

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Bibliografiske detaljer
Udgivet i:Ann Rheum Dis
Main Authors: Glatt, Sophie, Taylor, Peter C, McInnes, Iain B, Schett, Georg, Landewé, Robert, Baeten, Dominique, Ionescu, Lucian, Strimenopoulou, Foteini, Watling, Mark I L, Shaw, Stevan
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2019
Fag:
Rheumatoid Arthritis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691864/
https://ncbi.nlm.nih.gov/pubmed/31177099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-214943
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