Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

OBJECTIVE: To investigate the underlying mechanisms behind changes in glucose homeostasis with delivery of propionate to the human colon by comprehensive and coordinated analysis of gut bacterial composition, plasma metabolome and immune responses. DESIGN: Twelve non-diabetic adults with overweight...

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Vydáno v:Gut
Hlavní autoři: Chambers, Edward S, Byrne, Claire S, Morrison, Douglas J, Murphy, Kevin G, Preston, Tom, Tedford, Catriona, Garcia-Perez, Isabel, Fountana, Sofia, Serrano-Contreras, Jose Ivan, Holmes, Elaine, Reynolds, Catherine J, Roberts, Jordie F, Boyton, Rosemary J, Altmann, Daniel M, McDonald, Julie A K, Marchesi, Julian R, Akbar, Arne N, Riddell, Natalie E, Wallis, Gareth A, Frost, Gary S
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2019
Témata:
Gut Microbiota
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691855/
https://ncbi.nlm.nih.gov/pubmed/30971437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-318424
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