Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

OBJECTIVE: To investigate the underlying mechanisms behind changes in glucose homeostasis with delivery of propionate to the human colon by comprehensive and coordinated analysis of gut bacterial composition, plasma metabolome and immune responses. DESIGN: Twelve non-diabetic adults with overweight...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Chambers, Edward S, Byrne, Claire S, Morrison, Douglas J, Murphy, Kevin G, Preston, Tom, Tedford, Catriona, Garcia-Perez, Isabel, Fountana, Sofia, Serrano-Contreras, Jose Ivan, Holmes, Elaine, Reynolds, Catherine J, Roberts, Jordie F, Boyton, Rosemary J, Altmann, Daniel M, McDonald, Julie A K, Marchesi, Julian R, Akbar, Arne N, Riddell, Natalie E, Wallis, Gareth A, Frost, Gary S
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Gut Microbiota
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691855/
https://ncbi.nlm.nih.gov/pubmed/30971437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2019-318424
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