In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N(1),N(3)-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

A series of N(1),N(3)-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16 were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds 4–16 was assessed by the MTT assay method on colon, lung and breast tumour cell lines. Compo...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Enzyme Inhib Med Chem
Κύριοι συγγραφείς: Kassem, Asmaa F., Moustafa, Gaber O., Nossier, Eman S., Khalaf, Hemat S., Mounier, Marwa M., Al-Yousef, Suliman A., Mahmoud, Sabry Y.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Taylor & Francis 2019
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691786/
https://ncbi.nlm.nih.gov/pubmed/31286782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1613390
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