In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N(1),N(3)-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

A series of N(1),N(3)-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16 were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds 4–16 was assessed by the MTT assay method on colon, lung and breast tumour cell lines. Compo...

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Publicado en:J Enzyme Inhib Med Chem
Autores principales: Kassem, Asmaa F., Moustafa, Gaber O., Nossier, Eman S., Khalaf, Hemat S., Mounier, Marwa M., Al-Yousef, Suliman A., Mahmoud, Sabry Y.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691786/
https://ncbi.nlm.nih.gov/pubmed/31286782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1613390
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