Synthesis, Molecular Docking Studies, In Vitro Antimicrobial and Antifungal Activities of Novel Dipeptide Derivatives Based on N-(2-(2-Hydrazinyl-2-oxoethylamino)-2-oxoethyl)-Nicotinamide

A series of linear dipeptide derivatives (4–10) were prepared and evaluated as antimicrobial agents via the synthesis of N-(2-(2-hydrazinyl-2-oxoethylamino)-2-oxoethyl) nicotinamide (4). Compound 4 was reacted with 4-chlorobenzaldehyde or 4-hydroxybenzaldehyde, to give the hydrazones 5 and 6, respec...

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Publicado no:Molecules
Main Authors: Moustafa, Gaber, Khalaf, Hemat, Naglah, Ahmed, Al-Wasidi, Asma, Al-Jafshar, Nawal, Awad, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017860/
https://ncbi.nlm.nih.gov/pubmed/29584635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040761
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