Preclinical Targeting of Human Acute Myeloid Leukemia Using CD4-specific Chimeric Antigen Receptor (CAR) T Cells and NK Cells

Acute myeloid leukemia (AML) is an aggressive malignancy lacking targeted therapy due to shared molecular and transcriptional circuits as well as phenotypic markers with normal hematopoietic stem cells (HSCs). Identifying leukemia specific markers expressed on AML or AML subtypes for therapeutic tar...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Salman, Huda, Pinz, Kevin G., Wada, Masayuki, Shuai, Xiao, Yan, Lulu E., Petrov, Jessica C., Ma, Yupo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691696/
https://ncbi.nlm.nih.gov/pubmed/31413761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.28952
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