Preclinical Targeting of Human Acute Myeloid Leukemia Using CD4-specific Chimeric Antigen Receptor (CAR) T Cells and NK Cells

Acute myeloid leukemia (AML) is an aggressive malignancy lacking targeted therapy due to shared molecular and transcriptional circuits as well as phenotypic markers with normal hematopoietic stem cells (HSCs). Identifying leukemia specific markers expressed on AML or AML subtypes for therapeutic tar...

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Bibliografiske detaljer
Udgivet i:J Cancer
Main Authors: Salman, Huda, Pinz, Kevin G., Wada, Masayuki, Shuai, Xiao, Yan, Lulu E., Petrov, Jessica C., Ma, Yupo
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691696/
https://ncbi.nlm.nih.gov/pubmed/31413761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.28952
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