Preclinical Targeting of Human Acute Myeloid Leukemia Using CD4-specific Chimeric Antigen Receptor (CAR) T Cells and NK Cells

Acute myeloid leukemia (AML) is an aggressive malignancy lacking targeted therapy due to shared molecular and transcriptional circuits as well as phenotypic markers with normal hematopoietic stem cells (HSCs). Identifying leukemia specific markers expressed on AML or AML subtypes for therapeutic tar...

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Dades bibliogràfiques
Publicat a:J Cancer
Autors principals: Salman, Huda, Pinz, Kevin G., Wada, Masayuki, Shuai, Xiao, Yan, Lulu E., Petrov, Jessica C., Ma, Yupo
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691696/
https://ncbi.nlm.nih.gov/pubmed/31413761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.28952
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