Sex modulates the ApoE ε4 effect on brain tau deposition measured by (18)F-AV-1451 PET in individuals with mild cognitive impairment

The strongest genetic risk factor for Alzheimer's disease (AD) is the Apolipoprotein E type 4 allele (ApoE ε4). The interaction between sex and ApoE ε4 carrier status on AD risk remains an area of intense investigation. We hypothesized that sex modulates the relationship between ApoE ε4 carrier...

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Publicado en:Theranostics
Autores principales: Liu, Min, Paranjpe, Manish D, Zhou, Xin, Duy, Phan Q., Goyal, Manu S, Benzinger, Tammie L.S., Lu, Jie, Wang, Rongfu, Zhou, Yun
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691387/
https://ncbi.nlm.nih.gov/pubmed/31410194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35366
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