Sex modulates the ApoE ε4 effect on brain tau deposition measured by (18)F-AV-1451 PET in individuals with mild cognitive impairment

The strongest genetic risk factor for Alzheimer's disease (AD) is the Apolipoprotein E type 4 allele (ApoE ε4). The interaction between sex and ApoE ε4 carrier status on AD risk remains an area of intense investigation. We hypothesized that sex modulates the relationship between ApoE ε4 carrier...

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Bibliografische gegevens
Gepubliceerd in:Theranostics
Hoofdauteurs: Liu, Min, Paranjpe, Manish D, Zhou, Xin, Duy, Phan Q., Goyal, Manu S, Benzinger, Tammie L.S., Lu, Jie, Wang, Rongfu, Zhou, Yun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ivyspring International Publisher 2019
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691387/
https://ncbi.nlm.nih.gov/pubmed/31410194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.35366
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