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MicroRNA-20 induces methylation of hepatitis B virus covalently closed circular DNA in human hepatoma cells
Methylation was suggested to suppress the transcriptional activity of hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) in hepatocytes. This may be associated with its low replicative activity during the inactive stage of chronic HBV infection; however, the exact mechanisms of methylat...
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| Publié dans: | Mol Med Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6691198/ https://ncbi.nlm.nih.gov/pubmed/31257511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10435 |
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