Oxymatrine reverses epithelial-mesenchymal transition in breast cancer cells by depressing α(Ⅴ)β(3) integrin/FAK/PI3K/Akt signaling activation

PURPOSE: Oxymatrine, an alkaloid extracted from the Chinese herb Sophora flavescens Aiton, possesses anti-inflammatory, anti-immune, anti-hepatic fibrosis, and anti-cancer properties. However, the effects of oxymatrine on epithelial-mesenchymal transition (EMT) of breast cancer cells are still uncle...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Chen, Yan, Chen, Lin, Zhang, Jing-Yu, Chen, Zong-Yue, Liu, Ting-ting, Zhang, Yan-Yan, Fu, Ling-Yun, Fan, Shuang-Qin, Zhang, Min-Qin, Gan, Shi-quan, Zhang, Nen-ling, Shen, Xiang-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6691185/
https://ncbi.nlm.nih.gov/pubmed/31496729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S209056
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