Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis

Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene expression. Among the Rho GTPases, RhoA, Rac1 and Cdc42 are best characterized. The...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Zahra, Fatema Tuz, Sajib, Md Sanaullah, Ichiyama, Yusuke, Akwii, Racheal Grace, Tullar, Paul E., Cobos, Christopher, Minchew, Shelby A., Doçi, Colleen L., Zheng, Yi, Kubota, Yoshiaki, Gutkind, J. Silvio, Mikelis, Constantinos M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690958/
https://ncbi.nlm.nih.gov/pubmed/31406143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48053-z
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