HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study

Breast cancer treatment depends on human epidermal growth factor receptor-2 (HER2) status, which is often determined using dual probe fluorescence in situ hybridisation (FISH). Hereby, also loss and gain of the centromere of chromosome 17 (CEP17) can be observed (HER2 is located on chromosome 17). C...

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Publicat a:Sci Rep
Autors principals: Halilovic, Altuna, Verweij, Dagmar I., Simons, Annet, Stevens-Kroef, Marian J. P. L., Vermeulen, Susan, Elsink, Janet, Tops, Bastiaan B. J., Otte-Höller, Irene, van der Laak, Jeroen A. W. M., van de Water, Carlijn, Boelens, Oliver B. A., Schlooz-Vries, Margrethe S., Dijkstra, Jeroen R., Nagtegaal, Iris D., Tol, Jolien, van Cleef, Patricia H. J., Span, Paul N., Bult, Peter
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690925/
https://ncbi.nlm.nih.gov/pubmed/31406196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48212-2
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