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High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue

The KRAS mutation status predicts the outcome of treatment with epidermal growth factor receptor targeted agents, and therefore the testing for KRAS mutations has become an important diagnostic procedure. To optimize the quality of this test, we compared the results of the two most commonly used KRA...

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Detalhes bibliográficos
Main Authors: Tol, Jolien, Dijkstra, Jeroen R, Vink-Börger, Marianne E, Nagtegaal, Iris D, Punt, Cornelis JA, Van Krieken, Johan HJM, Ligtenberg, Marjolijn JL
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823003/
https://ncbi.nlm.nih.gov/pubmed/19453520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00788.x
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