Stimulation of P2Y11 receptor protects human cardiomyocytes against Hypoxia/Reoxygenation injury and involves PKCε signaling pathway

Sterile inflammation is a key determinant of myocardial reperfusion injuries. It participates in infarct size determination in acute myocardial infarction and graft rejection following heart transplantation. We previously showed that P2Y11 exerted an immunosuppressive role in human dendritic cells,...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Benoist, Lauriane, Chadet, Stéphanie, Genet, Thibaud, Lefort, Claudie, Heraud, Audrey, Danila, Maria D., Muntean, Danina M., Baron, Christophe, Angoulvant, Denis, Babuty, Dominique, Bourguignon, Thierry, Ivanes, Fabrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690895/
https://ncbi.nlm.nih.gov/pubmed/31406184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48006-6
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