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Peripheral myelin protein 22 modulates store-operated calcium channel activity, providing insights into Charcot-Marie-Tooth disease etiology

Charcot-Marie-Tooth (CMT) disease is a peripheral neuropathy associated with gene duplication and point mutations in the peripheral myelin protein 22 (PMP22) gene. However, the role of PMP22 in Schwann cell physiology and the mechanisms by which PMP22 mutations cause CMT are not well-understood. On...

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Publicat a:J Biol Chem
Autors principals: Vanoye, Carlos G., Sakakura, Masayoshi, Follis, Rose M., Trevisan, Alexandra J., Narayan, Malathi, Li, Jun, Sanders, Charles R., Carter, Bruce D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690708/
https://ncbi.nlm.nih.gov/pubmed/31213528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006248
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