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How a purine salvage enzyme singles out the right base
Two phosphoribosyltransferases in the purine salvage pathway exhibit exquisite substrate specificity despite the chemical similarity of their distinct substrates, but the basis for this discrimination was not fully understood. Ozeir et al. now employ a complementary biochemical, structural, and comp...
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Publicado no: | J Biol Chem |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690690/ https://ncbi.nlm.nih.gov/pubmed/31399535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H119.010025 |
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