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How a purine salvage enzyme singles out the right base

Two phosphoribosyltransferases in the purine salvage pathway exhibit exquisite substrate specificity despite the chemical similarity of their distinct substrates, but the basis for this discrimination was not fully understood. Ozeir et al. now employ a complementary biochemical, structural, and comp...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nagappa, Lakshmeesha Kempaiah, Balasubramanian, Sundaram, Balaram, Hemalatha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690690/
https://ncbi.nlm.nih.gov/pubmed/31399535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.H119.010025
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