DNA damage by lipid peroxidation products: implications in cancer, inflammation and autoimmunity

Oxidative stress and lipid peroxidation (LPO) induced by inflammation, excess metal storage and excess caloric intake cause generalized DNA damage, producing genotoxic and mutagenic effects. The consequent deregulation of cell homeostasis is implicated in the pathogenesis of a number of malignancies...

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Dettagli Bibliografici
Pubblicato in:AIMS Genet
Autori principali: Gentile, Fabrizio, Arcaro, Alessia, Pizzimenti, Stefania, Daga, Martina, Cetrangolo, Giovanni Paolo, Dianzani, Chiara, Lepore, Alessio, Graf, Maria, Ames, Paul R. J., Barrera, Giuseppina
Natura: Artigo
Lingua:Inglês
Pubblicazione: AIMS Press 2017
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690246/
https://ncbi.nlm.nih.gov/pubmed/31435505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/genet.2017.2.103
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