DNA damage by lipid peroxidation products: implications in cancer, inflammation and autoimmunity

Oxidative stress and lipid peroxidation (LPO) induced by inflammation, excess metal storage and excess caloric intake cause generalized DNA damage, producing genotoxic and mutagenic effects. The consequent deregulation of cell homeostasis is implicated in the pathogenesis of a number of malignancies...

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Detalhes bibliográficos
Publicado no:AIMS Genet
Main Authors: Gentile, Fabrizio, Arcaro, Alessia, Pizzimenti, Stefania, Daga, Martina, Cetrangolo, Giovanni Paolo, Dianzani, Chiara, Lepore, Alessio, Graf, Maria, Ames, Paul R. J., Barrera, Giuseppina
Formato: Artigo
Idioma:Inglês
Publicado em: AIMS Press 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690246/
https://ncbi.nlm.nih.gov/pubmed/31435505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/genet.2017.2.103
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