DNA damage by lipid peroxidation products: implications in cancer, inflammation and autoimmunity

Oxidative stress and lipid peroxidation (LPO) induced by inflammation, excess metal storage and excess caloric intake cause generalized DNA damage, producing genotoxic and mutagenic effects. The consequent deregulation of cell homeostasis is implicated in the pathogenesis of a number of malignancies...

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Publicado en:AIMS Genet
Autores principales: Gentile, Fabrizio, Arcaro, Alessia, Pizzimenti, Stefania, Daga, Martina, Cetrangolo, Giovanni Paolo, Dianzani, Chiara, Lepore, Alessio, Graf, Maria, Ames, Paul R. J., Barrera, Giuseppina
Formato: Artigo
Lenguaje:Inglês
Publicado: AIMS Press 2017
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6690246/
https://ncbi.nlm.nih.gov/pubmed/31435505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/genet.2017.2.103
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