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Highlight article: Long-term culture and characterization of patient-derived primary hepatocytes using conditional reprogramming
Cultivation of primary human hepatocytes (PHHs) often faces obstacles including failure of long-term in vitro culture, weak proliferation ability, rapid loss of liver-specific function and morphology, and tendency of fibrosis. Previous research focused on immortalization methods, such as telomerase...
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| Published in: | Exp Biol Med (Maywood) |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6690135/ https://ncbi.nlm.nih.gov/pubmed/31184925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370219855398 |
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