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Mapping hole hopping escape routes in proteins

A recently proposed oxidative damage protection mechanism in proteins relies on hole hopping escape routes formed by redox-active amino acids. We present a computational tool to identify the dominant charge hopping pathways through these residues based on the mean residence times of the transferring...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Teo, Ruijie D., Wang, Ruobing, Smithwick, Elizabeth R., Migliore, Agostino, Therien, Michael J., Beratan, David N.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689991/
https://ncbi.nlm.nih.gov/pubmed/31341081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906394116
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