Global Increase in Circular RNA Levels in Myotonic Dystrophy

Splicing aberrations induced as a consequence of the sequestration of muscleblind-like splicing factors on the dystrophia myotonica protein kinase transcript, which contains expanded CUG repeats, present a major pathomechanism of myotonic dystrophy type 1 (DM1). As muscleblind-like factors may also...

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Bibliographic Details
Published in:Front Genet
Main Authors: Czubak, Karol, Taylor, Katarzyna, Piasecka, Agnieszka, Sobczak, Krzysztof, Kozlowska, Katarzyna, Philips, Anna, Sedehizadeh, Saam, Brook, J. David, Wojciechowska, Marzena, Kozlowski, Piotr
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689976/
https://ncbi.nlm.nih.gov/pubmed/31428124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00649
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