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Quantitative Methods to Monitor RNA Biomarkers in Myotonic Dystrophy
Myotonic dystrophy type 1 (DM1) and type 2 (DM2) are human neuromuscular disorders associated with mutations of simple repetitive sequences in affected genes. The abnormal expansion of CTG repeats in the 3′-UTR of the DMPK gene elicits DM1, whereas elongated CCTG repeats in intron 1 of ZNF9/CNBP tri...
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| Gepubliceerd in: | Sci Rep |
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| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897446/ https://ncbi.nlm.nih.gov/pubmed/29651162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24156-x |
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