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Identification of evolutionary and kinetic drivers of NAD-dependent signaling

Nicotinamide adenine dinucleotide (NAD) provides an important link between metabolism and signal transduction and has emerged as central hub between bioenergetics and all major cellular events. NAD-dependent signaling (e.g., by sirtuins and poly–adenosine diphosphate [ADP] ribose polymerases [PARPs]...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bockwoldt, Mathias, Houry, Dorothée, Niere, Marc, Gossmann, Toni I., Reinartz, Ines, Schug, Alexander, Ziegler, Mathias, Heiland, Ines
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689970/
https://ncbi.nlm.nih.gov/pubmed/31341085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902346116
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