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Human long intrinsically disordered protein regions are frequent targets of positive selection

Intrinsically disordered regions occur frequently in proteins and are characterized by a lack of a well-defined three-dimensional structure. Although these regions do not show a higher order of structural organization, they are known to be functionally important. Disordered regions are rapidly evolv...

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Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Afanasyeva, Arina, Bockwoldt, Mathias, Cooney, Christopher R., Heiland, Ines, Gossmann, Toni I.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028134/
https://ncbi.nlm.nih.gov/pubmed/29858274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.232645.117
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