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Exosomes regulate neurogenesis and circuit assembly

Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits. We show that exosome treatment increases proliferation in developing neural cultures and in vivo in denta...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sharma, Pranav, Mesci, Pinar, Carromeu, Cassiano, McClatchy, Daniel R., Schiapparelli, Lucio, Yates, John R., Muotri, Alysson R., Cline, Hollis T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689941/
https://ncbi.nlm.nih.gov/pubmed/31320591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902513116
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