Exosomes regulate neurogenesis and circuit assembly

Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits. We show that exosome treatment increases proliferation in developing neural cultures and in vivo in denta...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sharma, Pranav, Mesci, Pinar, Carromeu, Cassiano, McClatchy, Daniel R., Schiapparelli, Lucio, Yates, John R., Muotri, Alysson R., Cline, Hollis T.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2019
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689941/
https://ncbi.nlm.nih.gov/pubmed/31320591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1902513116
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