A tumor-targeted immune checkpoint blocker

To direct checkpoint inhibition to the tumor microenvironment, while avoiding systemic immune activation, we have synthesized a bispecific antibody [norleucine4, d-Phe7]-melanocyte stimulating hormone (NDP-MSH)-antiprogrammed cell death-ligand 1 antibody (αPD-L1) by conjugating a melanocyte stimulat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Zhang, Yuhan, Fang, Changming, Wang, Rongsheng E., Wang, Ying, Guo, Hui, Guo, Chao, Zhao, Lijun, Li, Shuhong, Li, Xia, Schultz, Peter G., Cao, Yu J., Wang, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689898/
https://ncbi.nlm.nih.gov/pubmed/31332018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1905646116
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky