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The regulation of immune checkpoints by the hypoxic tumor microenvironment

The tumor microenvironment (TME) influences the occurrence and progression of tumors, and hypoxia is an important characteristic of the TME. The expression of programmed death 1 (PD1)/programmed death-ligand 1 (PDL1), cytotoxic T-lymphocyte-associated antigen 4 (CTLA4), and other immune checkpoints...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Hu, Min, Li, Yongfu, Lu, Yuting, Wang, Miao, Li, Yingrui, Wang, Chaoying, Li, Qin, Zhao, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8109006/
https://ncbi.nlm.nih.gov/pubmed/34012727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11306
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