Mild Hypothermia Ameliorates Anesthesia Toxicity in the Neonatal Macaque Brain

Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans extends from the third trimester of pregnancy to...

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Publicado en:Neurobiol Dis
Autores principales: Ikonomidou, Chrysanthy, Kirvassilis, George, Swiney, Brant S., Wang, Sophie H., Huffman, Jacob N., Williams, Sasha L., Masuoka, Kobe, Capuano, Saverio, Brunner, Kevin R, Crosno, Kristin, Simmons, Heather S, Mejia, Andres F., Turski, Christopher, Brambrink, Ansgar, Noguchi, Kevin K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689440/
https://ncbi.nlm.nih.gov/pubmed/31175984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104489
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