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Neurotoxic astrocytes express the D-serine synthesizing enzyme, serine racemase, in Alzheimer’s disease
Although β-amyloid plaques are a well-recognized hallmark of Alzheimer’s disease (AD) neuropathology, no drugs reducing amyloid burden have shown efficacy in clinical trials, suggesting that once AD symptoms emerge, disease progression becomes independent of Aβ production. Reactive astrocytes are an...
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| Publicado no: | Neurobiol Dis |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689433/ https://ncbi.nlm.nih.gov/pubmed/31212068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.104511 |
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