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Arsenic-induced apoptosis in the p53-proficient and p53-deficient cells through differential modulation of NFκB pathway

Arsenic is a well-known environmental carcinogen and an effective chemotherapeutic agent. The underlying mechanism of this dual-effect, however, is not fully understood. In this study, we applied mouse p53(+/+) and p53(−/−) cells to examine the NFκB pathway and proinflammatory cytokines after arseni...

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Detalhes bibliográficos
Publicado no:Food Chem Toxicol
Main Authors: Yin, Lei, Yu, Xiaozhong
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689409/
https://ncbi.nlm.nih.gov/pubmed/29944914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2018.06.053
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