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The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas

Neurofibromatosis type 1 (NF1) is a common tumor-predisposition disorder due to germline mutations in the tumor suppressor gene NF1 A virtually pathognomonic finding of NF1 is the plexiform neurofibroma (PN), a benign, likely congenital tumor that arises from bi-allelic inactivation of NF1 PN can un...

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Библиографические подробности
Опубликовано в: :	Oncogene
Главные авторы:	Pemov, A, Li, H, Patidar, R, Hansen, NF, Sindiri, S, Hartley, SW, Wei, JS, Elkahloun, A, Chandrasekharappa, SC, Boland, JF, Bass, S, Mullikin, JC, Khan, J, Widemann, BC, Wallace, MR, Stewart, DR
Формат:	Artigo
Язык:	Inglês
Опубликовано:	2017
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6689395/ https://ncbi.nlm.nih.gov/pubmed/28068329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.464
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The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas

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