Defining early hematopoietic-fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, Activin and BMP signaling

Distinct regions of the primitive streak (PS) have diverse potential to differentiate into several tissues, including the hematopoietic lineage originated from the posterior region of PS. Although various signaling pathways have been identified to promote the development of PS and its mesoderm deriv...

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Pubblicato in:J Cell Physiol
Autori principali: Shen, Jun, Lyu, Cuicui, Zhu, Yaoyao, Feng, Zicen, Zhang, Shuo, Hoyle, Dixie L., Ji, Guangzhen, Brodsky, Robert A., Cheng, Tao, Wang, Zack Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689260/
https://ncbi.nlm.nih.gov/pubmed/30740687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.28272
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