L-655,708 Does not Prevent Isoflurane-induced Memory Deficits in Old Mice

BACKGROUND: General anesthesia and increasing age are two main risk factors for postoperative cognitive dysfunction (POCD). Effective agents for the prevention or treatment of POCD are urgently needed. L-655,708, an inverse agonist of α5 subunit-containing γ-aminobutyric acid subtype A (α5GABA(A)) r...

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Published in:Transl Neurosci
Main Authors: Gao, Teng, Liu, Yue, Zhao, Zifang, Luo, Yuan, Wang, Lifang, Wang, Yongan, Yin, Yiqing
Format: Artigo
Language:Inglês
Published: De Gruyter 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689210/
https://ncbi.nlm.nih.gov/pubmed/31410301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/tnsci-2019-0032
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