Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma

BACKGROUND: Over the past decade, newly designed cancer therapies have not significantly improved the survival of patients diagnosed with Malignant Pleural Mesothelioma (MPM). Among a limited number of genes that are frequently mutated in MPM several of them encode proteins that belong to the HIPPO...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Pulito, Claudio, Korita, Etleva, Sacconi, Andrea, Valerio, Mariacristina, Casadei, Luca, Lo Sardo, Federica, Mori, Federica, Ferraiuolo, Maria, Grasso, Giuseppe, Maidecchi, Anna, Lucci, Jacopo, Sudol, Marius, Muti, Paola, Blandino, Giovanni, Strano, Sabrina
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689183/
https://ncbi.nlm.nih.gov/pubmed/31399037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1352-3
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