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Quantitative principles of cis-translational control by general mRNA sequence features in eukaryotes

BACKGROUND: General translational cis-elements are present in the mRNAs of all genes and affect the recruitment, assembly, and progress of preinitiation complexes and the ribosome under many physiological states. These elements include mRNA folding, upstream open reading frames, specific nucleotides...

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Veröffentlicht in:Genome Biol
Hauptverfasser: Li, Jingyi Jessica, Chew, Guo-Liang, Biggin, Mark Douglas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689182/
https://ncbi.nlm.nih.gov/pubmed/31399036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1761-9
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