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Quantitating translational control: mRNA abundance-dependent and independent contributions and the mRNA sequences that specify them
Translation rate per mRNA molecule correlates positively with mRNA abundance. As a result, protein levels do not scale linearly with mRNA levels, but instead scale with the abundance of mRNA raised to the power of an ‘amplification exponent’. Here we show that to quantitate translational control, th...
Shranjeno v:
| izdano v: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714229/ https://ncbi.nlm.nih.gov/pubmed/29040683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx898 |
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