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Expanding C–T base editing toolkit with diversified cytidine deaminases
Base editing tools for cytosine to thymine (C–T) conversion enable genome manipulation at single base-pair resolution with high efficiency. Available base editors (BEs) for C–T conversion (CBEs) have restricted editing scopes and nonnegligible off-target effects, which limit their applications. Here...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6689024/ https://ncbi.nlm.nih.gov/pubmed/31399578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11562-6 |
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