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HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N(6)-methyladenosine
Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress. By using an unbiased quantitative proteomic method, we uncover that treatment with three...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688989/ https://ncbi.nlm.nih.gov/pubmed/31399576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11552-8 |
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