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HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N(6)-methyladenosine
Small-molecule inhibitors for the 90-kDa heat shock protein (HSP90) have been extensively exploited in preclinical studies for the therapeutic interventions of human diseases accompanied with proteotoxic stress. By using an unbiased quantitative proteomic method, we uncover that treatment with three...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688989/ https://ncbi.nlm.nih.gov/pubmed/31399576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11552-8 |
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