Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse

Fibrosis may be a key factor in sensorimotor dysfunction in patients with chronic overuse‐induced musculoskeletal disorders. Using a clinically relevant rodent model, in which performance of a high demand handle‐pulling task induces tissue fibrosis and sensorimotor declines, we pharmacologically blo...

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Veröffentlicht in:J Orthop Res
Hauptverfasser: Barbe, Mary F., Hilliard, Brendan A., Delany, Sean P., Iannarone, Victoria J., Harris, Michele Y., Amin, Mamta, Cruz, Geneva E., Barreto‐Cruz, Yeidaliz, Tran, Ngih,  Day, Emily P., Hobson, Lucas J., Assari, Soroush, Popoff, Steven N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688947/
https://ncbi.nlm.nih.gov/pubmed/31041999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24337
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